List of EC numbers (EC 5)

This list contains a list of EC numbers for the fifth group, EC 5, isomerases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald.

EC 5.1: Epimerases and racemases

EC 5.1.1: Acting on Amino acids and Derivatives

EC 5.1.2: Acting on Hydroxy acids and Derivatives

EC 5.1.3: Acting on Carbohydrates and Derivatives

EC 5.1.99: Acting on Other Compounds

EC 5.2: cis-trans-Isomerases

EC 5.2.1: cis-trans Isomerases (only sub-subclass identified to date)

: maleate isomerase
: maleylacetoacetate isomerase
: Now known to be catalysed by a pathway involving , NADP-retinol dehydrogenase; , phosphatidylcholineÃ¢ÂÂretinol O-acyltransferase; , retinoid isomerohydrolase; and , 11-cis-retinol dehydrogenase.
: maleylpyruvate isomerase
: linoleate isomerase
: furylfuramide isomerase
: transferred to , retinoid isomerohydrolase
: peptidylprolyl isomerase
: farnesol 2-isomerase
: 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
: DELETED "4-hydroxyphenylacetaldehyde-oxime isomerase" – The existence of this enzyme has been called into question by one of the authors of the reference cited
: ÃÂ¶-carotene isomerase
: prolycopene isomerase
: ÃÂ²-carotene isomerase

EC 5.3: Intramolecular Oxidoreductases

EC 5.3.1: Interconverting Aldoses and Ketoses

: triose-phosphate isomerase
: deleted
: D-arabinose isomerase
: L-arabinose isomerase
: xylose isomerase
: ribose-5-phosphate isomerase
: mannose isomerase
: mannose-6-phosphate isomerase
: glucose-6-phosphate isomerase
: Now , glucosamine-6-phosphate deaminase
: deleted
: glucuronate isomerase
: arabinose-5-phosphate isomerase
: L-rhamnose isomerase
: D-lyxose ketol-isomerase
: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
: 5-dehydro-4-deoxy-D-glucuronate isomerase
: deleted: reaction is due to glucose-6-phosphate isomerase, in the presence of arsenate, or xylose isomerase
: Now , glutamineÃ¢ÂÂfructose-6-phosphate transaminase (isomerizing)
: ribose isomerase
: corticosteroid side-chain-isomerase
: hydroxypyruvate isomerase
: S-methyl-5-thioribose-1-phosphate isomerase
: phosphoribosylanthranilate isomerase
: L-fucose isomerase
: galactose-6-phosphate isomerase
: 6-phospho-3-hexuloisomerase
: D-sedoheptulose 7-phosphate isomerase
: ribose 1,5-bisphosphate isomerase
: 5-deoxy-glucuronate isomerase
: sulfoquinovose isomerase
: (4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase
: L-erythrulose 1-phosphate isomerase
: D-erythrulose 4-phosphate isomerase
: 2-dehydrotetronate isomerase
: D-apiose isomerase

EC 5.3.2: Interconverting Keto- and Enol-Groups

EC 5.4: Intramolecular Transferases

EC 5.4.1: Transferring Acyl Groups

: lysolecithin acylmutase
: Now , precorrin-8X methylmutase
: 2-methylfumaryl-CoA isomerase
: D-galactarolactone isomerase

EC 5.4.2: Phosphotransferases (Phosphomutases)

: Now recognized as two separate enzymes , phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) and , phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
: phosphoglucomutase (ÃÂ±-D-glucose-1,6-bisphosphate-dependent)
: phosphoacetylglucosamine mutase
: bisphosphoglycerate mutase
: phosphoglucomutase (glucose-cofactor)
: ÃÂ²-phosphoglucomutase
: phosphopentomutase
: phosphomannomutase
: phosphoenolpyruvate mutase
: phosphoglucosamine mutase
: phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
: phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
: phosphogalactosamine mutase

EC 5.4.3: Transferring Amino Groups

: deleted; this reaction was due to a mixture of (ornithine racemase) and (D-ornithine 4,5-aminomutase)
: lysine 2,3-aminomutase
: lysine 5,6-aminomutase
: Now included in , lysine 5,6-aminomutase
: D-ornithine 4,5-aminomutase
: tyrosine 2,3-aminomutase
: leucine 2,3-aminomutase
: glutamate-1-semialdehyde 2,1-aminomutase
: glutamate 2,3-aminomutase
: phenylalanine aminomutase (L-ÃÂ²-phenylalanine forming)
: phenylalanine aminomutase (D-ÃÂ²-phenylalanine forming)

EC 5.4.4: Transferring hydroxy groups

EC 5.4.99: Transferring Other Groups

EC 5.5: Intramolecular Lyases

EC 5.5.1: Intramolecular lyases (only sub-subclass identified to date)

EC 5.6: Isomerases altering macromolecular conformation

EC 5.6.1: Enzymes altering polypeptide conformation or assembly

EC 5.6.2: Enzymes altering nucleic acid conformation

EC 5.99: Other Isomerases

EC 5.99.1: Sole sub-subclass for isomerases that do not belong in the other subclasses

: thiocyanate isomerase
: Now , DNA topoisomerase
: Now , DNA topoisomerase (ATP-hydrolysing)
: 2-hydroxychromene-2-carboxylate isomerase