Germanicol synthase (, RsM1, (S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualenee mutase (cyclizing, germanicol-forming). This enzyme catalyses the following chemical reaction
The enzyme produces germanicol, beta-amyrin and lupeol.