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Outline of immunology

The following outline is provided as an overview of and topical guide to immunology:

Immunology – study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Essence of immunology

Immunology

Branches of immunology:

  1. General Immunology
  2. Basic Immunology
  3. Advanced Immunology
  4. Medical Immunology
  5. Pharmaceutical Immunology
  6. Clinical Immunology
  7. Environmental Immunology
  8. Cellular and Molecular Immunology
  9. Food and Agricultural Immunology

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* Testicular immunology - Testes
* Immunodermatology - Skin
* Intravascular immunology - Blood
* Osteoimmunology - Bone
* Mucosal immunology - Mucosal surfaces
:* Respiratory tract antimicrobial defense system - Respiratory tract
* Neuroimmunology - Neuroimmune system in the Central nervous system
* Ocularimmunology - Ocular immune system in the Eye
* Cancer immunology/Immunooncology - Tumors

History of immunology

History of immunology

General immunological concepts

* Immunity against:
:* Pathogens
:** Pathogenic bacteria
:** Viruses
:** Fungi
:** Protozoa
:* Parasites
:* Tumors
:* Allergens
:* Self-proteins
* Autoimmunity
* Alloimmunity
* Cross-reactivity
* Central tolerance
* Peripheral tolerance
* Clonal anergy
* Clonal deletion
* Tolerance in pregnancy
* Immunodeficiency
* Antigenicity
* Immunogen
* Superantigen
* Allergen
* Hapten
* Epitope
:* Linear
:* Conformational
:* Mimotope
* Tumor antigen
* Antigen-antibody interaction
* Affinity maturation
:* Somatic hypermutation
:* Clonal selection
* V(D)J recombination
:* Artemis complex
:* Recombination-activating gene
::* RAG1
::* RAG2
:* Recombination signal sequences
* Junctional diversity
* Immunoglobulin class switching
* Allelic exclusion
* Polyclonal response
* Opsonin

Components of the immune system

Immune system

  Adaptive immune system

Adaptive immune system

* Humoral immunity
:* Antibodies
::* Kinds of antibodies
:::* Monoclonal antibodies
:::* Polyclonal antibodies
:::* Autoantibody
:::* Microantibody
:::* Neutralizing antibody
::* Classification
:::* Allotype
:::* Isotype
:::* Idiotype
::* Functions
:::* Antibody opsonization
:::* Neutralisation
::* Regions
:::* Paratope
:::* Complementarity-determining region (CDRs)
:::* Hypervariable region
:::* Framework region
:::* Fab Region
:::* Fc Region
:* Polyclonal B cell response
* Cell-mediated immunity

  Innate immune system

Innate immune system

* Complement system
:* Classical complement pathway
:* Mannan-binding lectin pathway
:* Alternate complement pathway
:* Complement membrane attack complex
*Surface barriers – Physical or chemical barriers that prevent infection (i.e. skin, tears, mucus, saliva, Gastric acid, etc.)
:*Antimicrobial peptides
:*Defensins
:*Lysozyme
* Inflammation
:* Inflammatory reflex
:* Inflammasome
:* Granuloma
:* Acute-phase proteins
::* Amyloid
::* Positive
::* Negative

Organs of the immune system

Lymphatic system

  Primary lymphoid organs

Primary lymphoid organs

* Thymus - Site of T cell maturation
* Bone marrow - Site of haematopoiesis and B cell maturation

  Secondary lymphoid organs

Secondary lymphoid organs

* Spleen
** White pulp
** Red pulp
** Marginal zone
* Lymph nodes
* Mucosa-associated lymphoid tissue
:* Gut-associated lymphoid tissue
:* Bronchus-associated lymphoid tissue

Cells of the immune system

White blood cells

  Myeloid cells

* Granulocytes
** Neutrophils
** Eosinophils
** Basophils
**Mast cells
* Monocytes
* Macrophages
:* Histiocytes (Tissue resident macrophages)
::* Adipose tissue macrophages
::* Kupffer cell - Liver
::* Alveolar macrophage (Dust cell) - Lung
::* Langerhans cell - Skin
::* Dermal macrophage - Dermis
::* Microglia - CNS
::* Perivascular macrophage
::* Meningeal macrophage - Meninges
::* Hofbauer cell - Placenta
::* Osteoclasts - Bone
::* Bone marrow macrophage - Bone marrow
::* Marginal zone macrophage - Spleen
::* Metallophilic macrophage - Spleen
::* Red pulp macrophage - Splenic red pulp
::* Tingible body macrophage (White pulp macrophage) - Splenic white pulp
:* Giant cells
::* Foreign-body giant cell
::* Langhans giant cell
::* Touton giant cells
:* Epithelioid cells
:* Bone marrow-derived macrophages - Generated in vitro
*Dendritic Cells
:*Conventional Dendritic Cells
:*Plasmacytoid dendritic cells

  Lymphoid cells

Lymphoid cells

* B cells
** Plasma B cells
** Memory B cells
** B-1 cells
** B-2 cells (the conventional B cells most texts refer to)
** Marginal-zone B cells
** Follicular B cells
* T cells
** Naive T cells
** Helper T cells - Commonly termed CD4+ T cells
*** Th1 cells
*** Th2 cells
*** Th3 cells
*** Th17 cells
*** T<sub>FH</sub> cells - Follicular helper T cells
** Cytotoxic T cells - Commonly termed CD8+ T cells
** Memory T cells
** Regulatory T cells
** Natural Killer T cells (NKT cells)
** γδ T cells
** Mucosal associated invariant T cells
* Innate lymphoid cells (ILC)
** Group 1 ILC
*** Natural killer cells (NK cells)
** Group 2 ILC
*** Nuocyte
** Group 3 ILC
*** Lymphoid Tissue inducer cells (LTi cells)

&nbsp;&nbsp;Others

(Non-hematopoietic cells with immune functions)
* Stromal cells
:* Lymph node stromal cells
:* Follicular dendritic cells
* Epithelial cells
* Pericytes
* Microfold cells (M cells)

&nbsp;&nbsp;Hematopoiesis

* Lymphopoiesis
:* Lymphoblast
:* Prolymphocyte
::* T cell development
:::* Thymocyte
::* B cell development
:::* Pre-pro-B cell
:::* Early pro-B cell
:::* Late pro-B cell
:::* Large pre-B cell
:::* Small pre-B cell
:::* Immature B cell
* Myelopoiesis
:* Common myeloid progenitor (CFU-GEMM)
::* Granulocyte-macrophage progenitor (CFU-GM)
:::* Granulopoiesis
::::* Myeloblast (CFU-G)
::::* Promyelocyte
::::* Myelocyte
::::* Metamyelocyte
::::* Band cell
:::* Monocytopoiesis
::::* Monoblast (CFU-M)
:::::* CFU-DL - Dendritic cell / Langerhans cell precursor
::::* Promonocyte
::* CFU-Baso (Basophil precursor)
::* CFU-Eos (Eosinophil precursor)
::* Megakaryocyte-erythroid progenitor cell (MEP)
:::* Megakaryocytopoiesis
::::* CFU-Meg
::::* Megakaryoblast
::::* Promegakaryocyte
::::* Megakaryocyte
::::* Thrombopoiesis
:::::* Thrombocyte (Platelets)
:::* Erythropoiesis
::::* Proerythroblast
::::* Normoblast
::::* Reticulocyte
::* CFU-Mast
:::* Mast cell precursors

Molecules of the immune system

Immune receptors

&nbsp;&nbsp;&nbsp;Antigen receptors

* B cells
:* Antigen receptor - B cell receptor (BCR)
:* Subunits- Immunoglobulin heavy chain / Immunoglobulin light chain
:* Co-receptors
::* Stimulatory
:::* CD21
:::* CD19
:::* CD81
::* Inhibitory
:::* CD22
:* Accessory molecule (CD79)
::* Ig-α (CD79A)
::* Ig-β (CD79B)
* T cells
:* Antigen receptor - T cell receptor (TCR)
::* Subunits - TRA@ / TRB@ / TRD@ / TRG@
:* Co-receptors
::* CD8 (CD8α / CD8β)
::* CD4
:* Accessory molecules
::* CD3
:::* Subunits - one CD3γ / one CD3δ / two CD3ε
::* ζ-chain (CD247, CD3ζ, TCRζ)

&nbsp;&nbsp;&nbsp;Pattern recognition receptors (PRRs)

Pattern recognition receptor

* Membrane-bound PRRs
:* Toll-like receptors (TLRs)
:* C-type lectin receptors (CLRs)
::
::* Group 1 CLRs - Mannose receptors
::* Group 2 CLRs - Asialoglycoprotein receptor family
:::* Dectin 1 subfamily
:::* DCIR subfamily
:* Scavenger receptors
::* Class A - Trimers
::* Class B - Two transmembrane domains
::* Others
:* Formyl peptide receptors (FPRs)
* Cytoplasmic PRRs
:* NOD-like receptors (NLRs)
::* NLRA (A for acidic transactivating domain)
:::* CIITA
::* NLRB (B for BIR, or Inhibitor of apoptosis domain)
:::* NAIP
::* NLRC (C for CARD domain)
::* NLRP (P for Pyrin domain)
::* NLRX
:::* NLRX1
:* RIG-I-like receptors (RLRs) - Intracellular sensors of viral replication by direct interaction with dsRNA
* Secreted PRRs
:* Complement system (see complement proteins section)
:* Collectins
:* Peptidoglycan recognition proteins (PGRPs)
:* Ficolins

&nbsp;&nbsp;&nbsp;Complement receptors

Complement receptor

* CR1 (CD35)
* CR2 (CD21)
* CR3 - Heterodimer: CD11b / CD18
* CR4 - Heterodimer: CD11c / CD18
* CRIg (Complement receptor of the immunoglobulin family)
* Anaphylatoxin receptors
:* C3a receptor
:* C5a receptor (CD88)
:* C5AR2

&nbsp;&nbsp;&nbsp;Fc receptors

Fc receptor

* Fc-gamma receptors (FcγR)
:* FcγRI (CD64)
:* FcγRIIA (CD32A)
:* FcγRIIB (CD32B)
:* FcγRIIIA (CD16a)
:* FcγRIIIB (CD16b)
:* FcγRT (Neonatal Fc receptor)
* Fc-alpha receptors (FcαR)
:* FcαRI (CD89, FCAR)
:* Fcα/μR
* Fc-epsilon receptors (FcεR)
:* FcεRI - Tetramer: FCER1A / FCER1B / two FCER1G
:* FcεRII (CD23)
* Secreted Fc receptors
:* Polymeric immunoglobulin receptor (poly-Ig)
* Fc receptor-like molecules

&nbsp;&nbsp;&nbsp;Cytokine receptors

Cytokine receptor

* Type I cytokine receptors (Hemopoietin receptors) - Share extracellular WSXWS motif, Grouped by common receptor subunits
:*Common gamma chain (γ-chain, CD132)
::* IL2R - Heterotrimer: IL2RA (CD25) / IL2RB (CD122) / γ<sub>c</sub>
::* IL4R / IL13R - Heterodimer: IL4RA / (IL13RA1/IL13RA2)
::* IL7R - Heterodimer: IL7RA (CD127) / γ-chain
::* IL9R - Heterodimer: IL9R / γ-chain
::* IL15R - Heterotrimer: IL15RA / IL2RB / γ-chain
::* IL21R - Heterodimer: IL21R / γ-chain
:*Common beta chain (β-chain, CD131)
::* IL3R - Heterodimer: IL3RA / β-chain
::* IL5R - Heterodimer: IL5RA / β-chain
::* GM-CSFR (CD116) - Heterdimer: GM-CSFRA / β-chain
:* Common gp130 subunit (gp130, CD130)
::* IL6R - Heterodimer: IL6RA / gp130
::* IL11R - Heterodimer: IL11RA / gp130
::* IL27R - Heterodimer: IL27RA / gp130
::* OSMR - Heterodimer: OSMR / gp130
::* LIFR (CD118) - Heterodimer: LIFR / gp130
:* IL12 receptor beta 1 subunit (IL12RB1)
::* IL12R - Heterodimer: IL12RB1 / IL12RB2
::* IL23R - Heterodimer: IL23RA / IL12RB1
:* Others
::* EPOR (Erythropoietin receptor) - Homodimer
::* G-CSFR (CD114) - Homodimer upon ligand binding
::* MPL (CD110, Thrombopoietin receptor) - Homodimer upon ligand binding
::* GHR (Growth hormone receptor) - Homodimer upon ligand binding
::* PRLR (Prolactin receptor)
* Type II cytokine receptor - Lack WSXWS motif
:* Interferon receptors
::* Interferon-α/β receptor (IFNAR) - Heterodimer: IFNAR1 / IFNAR2
::* Interferon-γ receptor (IFNGR) - Heterodimer: IFNGR1 / IFNGR2
:* Interleukin receptors
::* IL10R - Heterodimer: IL10RA / IL10RB
::* IL20R - Heterodimer: IL20RA / IL20RB
::* IL22R - Heterodimer: IL22RA1 / IL10RB
::* IL28R - Heterodimer: IL28RA / IL10RB
* Immunoglobulin superfamily (Some members)
:* CSF1
:* CD117 (c-KIT)
:* IL1 receptor family (IL1R)
::* IL1R type 1 (CD121a)
::* IL1R type 2 (CD121b)
::* IL1R accessory protein (IL1RAP)
::* IL1RL1 (IL33R, ST2)
:* IL18R - Heterodimer: IL18R1 / IL18RAP
* IL17 family
:* IL17RA
:* IL17RB
:* IL17RC
:* IL17RD
:* IL17RE
* Tumor necrosis factor (TNF) receptor family - Trimeric cytokine receptors
::* TNFRSF1A (CD120a)
::* TNFRSF1B (CD120b)
::* TNFRSF3 (Lymphotoxin βR)
::* TNFRSF4 (CD134, OX40)
::* TNFRSF5 (CD40)
::* TNFRSF6 (FAS)
::* TNFRSF6B
::* TNFRSF7 (CD27)
::* TNFRSF8 (CD30)
::* TNFRSF9 (CD137)
::* TNFRSF10A (CD261)
::* TNFRSF10B (CD262)
::* TNFRSF10C (CD263)
::* TNFRSF10D (CD264)
::* TNFRSF11A (CD265, RANK)
::* TNFRSF11B (Osteoprotegerin)
::* TNFRSF12A (CD266)
::* TNFRSF13B (CD267)
::* TNFRSF13C
::* TNFRSF14 (CD268)
::* TNFRSF16 (LNGRF)
::* TNFRSF17 (CD269)
::* TNFRSF18
::* TNFRSF19
::* TNFRSF21
::* TNFRSF25
::* TNFRSF27
* Chemokine receptors - 7-transmembrane G protein-coupled receptors
:* CC chemokine receptors (CCRs)
::* CCR1
::* CCR2
::* CCR3
::* CCR4
::* CCR5
::* CCR6
::* CCR7
::* CCR8
::* CCR9
::* CCR10
:* CXC chemokine receptors (CXCRs)
::* CXCR1
::* CXCR2
::* CXCR3
::* CXCR4
::* CXCR5
::* CXCR6
::* CXCR7
:* C chemokine receptors (XCRs)
::* XCR1
:* CX<sub>3</sub>C chemokine receptors (CX<sub>3</sub>CRs)
::* CX<sub>3</sub>CR1 (Fractalkine receptor)
* TGF beta receptors - Single transmembrane pass serine/threonine kinase receptors
:* TGFBR1
:* TGFBR2
:* TGFBR3

&nbsp;&nbsp;&nbsp;Natural killer cell receptors

Natural killer cell receptors

* Killer activation receptors (KARs)
:* Natural cytotoxicity receptors (NCRs)
:* Natural killer group 2 receptors (NKG2s)
:* Activating KIRs
::* KIR2DS1
* Killer inhibitory receptors (KIRs)
:* Two domains, long cytoplasmic tail
:* Two domains, short cytoplasmic tail
:* Three domains, long cytoplasmic tail
:* Three domains, short cytoplasmic tail
::* KIR3DS1

&nbsp;&nbsp;&nbsp;Others

* Leukocyte immunoglobulin-like receptors (LILRs)
:* LILR subfamily A
:* LILR subfamily B
* Eicosanoid receptors

Antibodies

Antibodies

Cytokines

Cytokine

* CC chemokines
:* CCL1
:* CCL2
:* CCL3
:* CCL4
:* CCL5
:* CCL6
:* CCL7
:* CCL8
:* CCL9/CCL10
:* CCL11
:* CCL12
:* CCL13
:* CCL14
:* CCL15
:* CCL16
:* CCL17
:* CCL18
:* CCL19
:* CCL20
:* CCL21
:* CCL22
:* CCL23
:* CCL24
:* CCL25
:* CCL26
:* CCL27
:* CCL28
* CXC chemokines
:* CXCL1
:* CXCL2
:* CXCL3
:* CXCL4
:* CXCL5
:* CXCL6
:* CXCL7
:* CXCL8
:* CXCL9
:* CXCL10
:* CXCL11
:* CXCL12
:* CXCL13
:* CXCL14
:* CXCL15
:* CXCL16
:* CXCL17
* C chemokines
:* XCL1
:* XCL2
* CX<sub>3</sub>C chemokines
:* CX<sub>3</sub>CL1 (Fractalkine, Neurotactin)
* IL1A
* IL1B
* IL1RA
* IL2
* IL3
* IL4
* IL5
* IL6
* IL7
* IL8
* IL9
* IL10
* IL11
* IL12
* IL13
* IL14
* IL15
* IL16
* IL17A
* IL17F
* IL18
* IL19
* IL20
* IL21
* IL22
* IL23
* IL24
* IL25
* IL26
* IL27
* IL28A
* IL28B
* IL29
* IL30
* IL31
* IL32
* IL33
* IL34
* IL35
* IL36A
* IL36B
* IL36G
* IL36RA
* IL37
* TSLP
* LIF (Leukemia inhibitory factor)
* OSM (Oncostatin M)
* TNFA
* TNFB (Lymphotoxin-α)
* TNFC (Lymphotoxin-β)
* TNFSF4 (OX40L)
* TNFSF5 (CD40L)
* TNFSF6 (FasL)
* TNFSF7 (CD70, CD27L)
* TNFSF8 (CD153, CD30L)
* TNFSF9 (4-1BBL)
* TNFSF10 (TRAIL)
* TNFSF11 (RANK-L, OPG-L)
* TNFSF12 (TWEAK)
* TNFSF13 (APRIL, CD256)
* TNFSF13B (BAFF, CD257)
* TNFSF14 (LIGHT, CD258)
* TNFSF15 (VEGI)
* TNFSF18
* EDA
* CSF1 (M-CSF)
* CSF2 (GM-CSF)
* CSF3 (G-CSF)

MHCs

Major histocompatibility complex

Complement proteins

  • Early stage (divided by pathway)
* Classical complement pathway
:* C1Q complex - C1R / C1S
:* C4 - C4a
:* C2
* Mannan-binding lectin pathway
:* MASP1 / MASP2
:* Mannan-binding lectin
* Alternative complement pathway
:* Factor B
:* Factor D
:* Factor P (Properdin)
  • Middle stage
* C3 - C3a / C3b / iC3b
* C5 - C5a
* C3-convertase
* C5-convertase
  • Late stage
* Membrane attack complex (MAC)
:* C6
:* C7
:* C8
:* C9
  • Complement pathway inhibitors
* C1-inhibitor - Classical, Lectin, Alternate
* Decay-accelerating factor (CD59) - Classical, Lectin, Alternate
* Factor I - Classical, Lectin, Alternate
* C4BP - Classical, Lectin
* Factor H - Alternate

Antimicrobial peptides

Antimicrobial peptides

Transcription factors

  • T-bet - T<sub>H</sub>1 differentiation
  • GATA3 - T<sub>H</sub>2 differentiation
  • RORγT - T<sub>H</sub>17 differentiation
  • BCL6 - T<sub>FH</sub> differentiation
  • FoxP3 - T<sub>reg</sub> differentiation

Signaling pathways

Cell adhesion molecules (CAMs)

Cell adhesion molecules

* Alpha subunits
* Beta subunits
* Dimers
:* Cytoadhesin receptor
::* Integrin alpha6beta4
::* Glycoprotein IIb/IIIa - Heterodimer: ITGA2B / ITGB3
:* Fibrinogen receptor
::* Macrophage-1 antigen (CR3) - Heterodimer: CD11b / CD18
:* Fibronectin receptor:
::* Integrin alpha2beta1
::* Integrin alpha4beta1
::* Integrin alpha5beta1
:* Leukocyte-adhesion receptor:
::* LFA-1 - Heterodimer: CD11a / CD18
::* Macrophage-1 antigen (CR3) - Heterodimer: CD11b / CD18
::* Integrin alphaXbeta2 (CR4) - Heterodimer: CD11c / CD18
:* Very late antigen receptor:
::* Integrin alpha1beta1
::* Integrin alpha2beta1
::* Integrin alpha3beta1
::* VLA-4 - Heterodimer: CD49d / CD29
::* Alpha-5 beta-1
::* Integrin alpha6beta1
:* Vitronectin receptor:
::* Alpha-v beta-3
::* Alpha-v beta-5
:* SynCAMs - Synaptic cell adhesion molecules
:* NCAMs - Neural cell adhesion molecules
:* Intercellular adhesion molecules (ICAMs)
:* VCAM-1 (CD106)
:* PECAM-1 (CD31)
:* L1 family
:* SIGLEC family - Sialic acid binding lectins
:* CTX family
:* Nectins
:* CD2 family
::* CD2
::* CD58
::* Signaling lymphocytic activation molecules (SLAMs)
* E-selectin
* L-selectin
* P-selectin
  • Others
* Lymphocyte homing receptors
:* CD34
:* GLYCAM-1
:* Addressin (MAdCAM-1)
* CD44
* Carcinoembryonic antigens
* CD24
* CD44
* CD146
* CD164

Others

* CD80 - Expressed by APCs
* CD86 - Expressed by APCs
* CD28 family receptors
:* CD28 - Expressed by T Cells
:* CD278 (ICOS) - Homodimer, expressed by T Cells
:* CTLA-4 (CD152)
:* PD-1 (CD279)

Immune system disorders

Immune disorder

Hypersensitivity and Allergy

* Type 1 hypersensitivity / Allergy / Atopy
:* Foreign (Allergen)
::* Atopic eczema
::* Allergic urticaria
::* Allergic rhinitis (Hay fever)
::* Allergic asthma
::* Anaphylaxis
::* Food allergy
:::* Milk allergy
:::* Egg allergy
:::* Peanut allergy
:::* Tree nut allergy
:::* Seafood allergy
:::* Soy allergy
:::* Wheat allergy
:::* Garlic allergy
::* Penicillin allergy
* Type 2 hypersensitivity / Antibody-dependent cell-mediated cytotoxicity (ADCC)
:* Foreign
::* Pernicious anemia
::* Hemolytic disease of the newborn
:* Autoimmune
::* Cytotoxic
:::* Autoimmune hemolytic anemia
:::* Idiopathic thrombocytopenic purpura
:::* Bullous pemphigoid
:::* Pemphigus vulgaris
:::* Rheumatic fever
:::* Goodpasture's syndrome
::* Type 5 / Receptor mediated
:::* Graves' disease
:::* Myasthenia gravis
* Type 3 hypersensitivity / Immune complex
:* Foreign
::* Henoch–Schönlein purpura
::* Hypersensitivity vasculitis
::* Reactive arthritis
::* Farmer's lung
::* Post-streptococcal glomerulonephritis
::* Serum sickness
::* Arthus reaction
:* Autoimmune
::* Systemic lupus erythematosus
::* Subacute bacterial endocarditis
::* Rheumatoid arthritis
* Type 4 hypersensitivity (Delayed-Type Hypersensitivity)
:* Foreign
::* Allergic contact dermatitis
::* Mantoux test
:* Autoimmune
::* Diabetes mellitus type 1
::* Hashimoto's thyroiditis
::* Guillain–Barré syndrome
::* Multiple sclerosis
::* Coeliac disease
::* Giant-cell arteritis
:* GVHD (Graft-versus-host disease)
::* Transfusion-associated graft versus host disease
* Unknown/Multiple types
:* Foreign
::* Hypersensitivity pneumonitis
::* Allergic bronchopulmonary aspergillosis
::* Transplant rejection
::* Latex allergy (I+IV)
:* Autoimmune
::* Sjögren's syndrome
::* Autoimmune hepatitis
::* Autoimmune polyendocrine syndrome (APS1 / APS2)
::* Autoimmune adrenalitis
::* Systemic autoimmune disease

Immunodeficiency

Immunodeficiency

* Primary immunodeficiency
* Acquired immunodeficiency
* Complement deficiency

Cancers of the immune system

Myeloid diseases

Inflammatory diseases

* Sepsis
* Inflammatory bowel disease (IBD)
* Cytokine storm

Immunoproliferative immunoglobulin disorders

Immunoproliferative immunoglobulin disorders

Lymphatic organ disease

Immunologic techniques and tests

* Rabbit hybridoma
* Developmental studies hybridoma bank

Immunology and health

* Activation immunotherapy
:* Cancer immunotherapy
:* Autologous immune enhancement therapy
* Immunosuppression
:* Sublingual immunotherapy
:* Allergen immunotherapy
:* Immunosuppressive drug
* Active immunotherapy
* Passive immunity
:* Temporarily induced immunity
:* Adoptive immunity
* Vaccine-naive
* Vaccine
* Herd immunity
* Adjuvant
* Allotransplant
* Transplant rejection

Immunologists

List of immunologists

Immunology lists

References

External links