Interferon gamma receptor 2 also known as IFN-óR2 is a protein which in humans is encoded by the IFNGR2 gene.
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a multimer of two IFN-óR1 chains (encoded by IFNGR1) and two IFN-óR2 chains.
Defects in IFNGR2 are a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. All known mutations in IFNGR2 are collected in the IFNGR2 mutation database.