This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed with the condition. Each disorder is also categorized by its acceptance as an autoimmune condition into four levels: confirmed, probable, possible, and uncertain. This classification is based on the current scientific consensus and reflects the level of evidence supporting the autoimmune nature of the disorder. Lastly, the prevalence rate, specifically in the United States, is included to give a sense of how common each disorder is within the population.
The integumentary system, composed of the skin, hair, nails, and associated glands, serves as a protective barrier between the body and the environment. It also plays a critical role in regulating body temperature and maintaining fluid balance.
The reproductive system is responsible for the production and regulation of sex hormones, the formation of germ cells, and the nurturing of fertilized eggs. In women, it includes structures such as ovaries, fallopian tubes, a uterus, and a vagina, while in men, it includes testes, vas deferens, seminal vesicles, prostate, and the penis. Autoimmune diseases of the reproductive system can affect both male and female fertility and reproductive health.
These autoimmune diseases are primarily associated with the muscles, joints and neuromuscular function.
This list includes conditions that are not diseases, but symptoms or syndromes common to autoimmune disease.
At this time, there is not sufficient evidence to indicate that the diseases in the following table are caused by autoimmunity. This section is included because some of these conditions are immune-related but frequently confused with autoimmune diseases. Others are conditions that have been historically speculated as autoimmune due to overlapping symptoms like inflammation, but have been reclassified or excluded based on current research.