1,4-Dicyanobenzene is an organic compound with the formula C<sub>6</sub>H<sub>4</sub>(CN)<sub>2</sub>. Two other isomers exist, phthalonitrile and isophthalonitrile. All three isomers are produced commercially by ammoxidation of the corresponding xylene isomers. 1,4-Dicyanobenzene is a colorless or white solid with low solubility in water. Hydrogenation of isophthalonitrile affords p-xylylenediamine.
1,4-dicyanobenzene is electrochemically active, forming a stable persistent radical at anodes. For this reason, it has been used as a catalyst for automated reaction discovery, testing whether other species are redox active.
The (rat, oral) is 6400 mg/kg.