Isophthalonitrile is an organic compound with the formula C<sub>6</sub>H<sub>4</sub>(CN)<sub>2</sub>. Two other isomers exist, phthalonitrile and terephthalonitrile. All three isomers are produced commercially by ammoxidation of the corresponding xylene isomers. Isophthalonitrile is a colorless or white solid with low solubility in water. Hydrogenation of isophthalonitrile affords m-xylylenediamine, a curing agent in epoxy resins and a component of some urethanes.
The of isophthalonitrile is 288 mg/kg (rat, oral).