Salutaridine, also known as floripavine, is an alkaloid that is present in the morphinan alkaloid pathway of opium poppy, Papaver somniferum.
It is produced by the enzyme salutaridine synthase that catalyzes the chemical reaction from its precursor (R)-reticuline:
The enzyme uses reduced nicotinamide adenine dinucleotide phosphate (NADPH) as its cofactor.
Salutaridine is converted to salutaridinol by the enzyme salutaridine reductase (NADPH).