Shikarpur district (, ), is a district in Larkana Division of Sindh province in Pakistan.
The city of Shikarpur is the district headquarters. There are 4 talukas: Lakhi, Garhi Yasin, Khanpur Tehsil and Shikarpur Tehsil itself. It is spread over an area of 2,512 km<sup>2</sup>.
Shikarpur district borders Larkana, Jacobabad, Khairpur and Sukkur. Two National Highways (N-65 & N-55) intersect the city of Shikarpur making it the junction points of 4 provinces.
The district of Shikarpur is sub-divided into four Tehsils these are:
As of the 2023 census, Shikarpur district has 214,824 households and a population of 1,386,330. The district has a sex ratio of 102.20 males to 100 females and a literacy rate of 43.70%: 52.59% for males and 34.65% for females. 514,189 (37.09% of the surveyed population) are under 10 years of age. 318,738 (22.99%) live in urban areas.
The majority religion is Islam, with 98.21% of the population. Hinduism (including those from Scheduled Castes) is practiced by 1.51% of the population, a majority of whom live in urban areas.
At the time of the 2023 census, 97.14% of the population spoke Sindhi and 1.29% Brahui as their first language.