Larkana Division () is an administrative division of the Sindh Province of Pakistan. It was created in 1980 by bifurcation of Sukkur Division. In 2000 abolished by General Pervaiz Musharraf rule but Sindh government restored it again on 11 July 2011. CNIC code of Larkana Division is 43.
Larkana is the divisional headquarters of Larkana Division. It comprises the following districts:
According to 2023 census, Larkana division had a population of 7,093,706 roughly equal to the population of Serbia or the US state of Massachusetts.