Scott Run is a long 2nd order tributary to Cross Creek in Brooke County, West Virginia.
Scott Run rises about 1.5 miles southeast of Eldersville, Pennsylvania, in Washington County and then flows southwest into West Virginia to join Cross Creek at Scott Run, West Virginia.
Scott Run drains of area, receives about 40.3 in/year of precipitation, has a wetness index of 322.78, and is about 53% forested.