Sappingtons Run is a long 1st order tributary to Harmon Creek in Brooke County, West Virginia. This is the only stream of this name in the United States.
Sappingtons Run rises about 2 miles west of Colliers, West Virginia, and then flows north and northeast to join Harmon Creek at Weirton.
Sappingtons Run drains of area, receives about 40.1 in/year of precipitation, has a wetness index of 300.63, and is about 76% forested.