San Colombano Certenoli () is a comune (municipality) in the Metropolitan City of Genoa in the Italian region Liguria, located about east of Genoa. It is the largest municipality in the Val Fontanabuona.
San Colombano Certenoli borders the following municipalities: Borzonasca, Carasco, Coreglia Ligure, Leivi, Mezzanego, Orero, Rapallo, Rezzoaglio, Zoagli.