SCQ1

(S)-SCQ1 is a drug which acts as a potent and selective antagonist for the 5-HT_2B and 5-HT_2C serotonin receptors, but with only modest affinity for the closely related 5-HT_2A receptor and other targets such as 5-HT₇. Since most currently available 5-HT₂ class ligands have relatively poor selectivity and bind to all three subtypes, the selectivity of (S)-SCQ1 is expected to be useful for studying 5-HT_2A receptor mediated responses in the absence of 5-HT_2B and 5-HT_2C activation.

See also

• SB-206553
• SB-242,084
• Z3517967757

References