Northeast Savo or North Eastern Savonia () is a sub-region of Finland. It is an administrative subdivision of the region of North Savo.
The region of Northeast Savo was named a region of sudden structural change during 2008 to 2010, after Stromsdal, a major employer in the region, went bankrupt.
Northeastern Savo previously comprised five municipalities: Juankoski, Kaavi, Nilsiä, Rautavaara, and Tuusniemi.
On 1 January 2013, Nilsiä was incorporated into the city of Kuopio, a part of the Kuopio sub-region, and was thus removed from Northeastern Savo.
On 1 January 2017, Juankoski was incorporated into the city of Kuopio. With the removal of Juankoski from the Northeastern Savo sub-region, the land connection between Rautavaara and the rest of the sub-region was broken.
The sub-region currently comprises the municipalities of Kaavi, Rautavaara, and Tuusniemi.
The sub-region had a population of 19,837 in 2011. In December 2021, the population was 6,711.