Malta selected their Junior Eurovision entry for 2010 through Junior Eurosong, a national final consisting of 20 songs. The winner was Nicole Azzopardi, with the song "Knock Knock!...Boom! Boom!"
Azzopardi competed for Malta at the Junior Eurovision Song Contest 2010, held on 20 November in Minsk, Belarus, finishing 13th out of 14 entries.
The final took place on 4 September 2010. Twenty entries competed and the votes of a six-member jury panel (6/7) and the results of public televoting (1/7) determined the winner.
The six members of the jury that evaluated the entries during the final consisted of: