Marco De Gasperi (born 5 April 1977) is an Italian male mountain runner, sky runner and long-distance runner.
He won five gold medals at senior level (from 1997 to 2007) and one at junior level (1996), at the World Mountain Running Championships. At European level he won 5 medals individual (1 gold, 2 silver, 2 bronze) and 6 gold medal with the national team at the European Mountain Running Championships from 2002 to 2008.
His partner is the Italian mountain running champion Elisa Desco. They have two daughters, Lidia (2011) and Cecilia (2017).