Luca Mazzone (born 3 May 1971) is an Italian paralympic cyclist and before para swimmer who won eight medals at the Summer Paralympics (3 gold and 3 silver in cycling, 2 silver in swimming).
He competed in five Paralympics, three in Swimming (2000, 2004, 2008) and two in Cycling (2016, 2020). He also won 18 world titles in cycling.