List of disease outbreaks in the United States

This is a list of notable disease outbreaks in the United States:

1700s

• 1775–1782 North American smallpox epidemic
• 1789–1790 influenza epidemic
• 1793 Philadelphia yellow fever epidemic

1800s

• 1837 Great Plains smallpox epidemic
• 1849-1850 Tennessee cholera epidemic
• 1853 yellow fever epidemic
• 1862 Pacific Northwest smallpox epidemic
• 1876 yellow fever epidemic
• 1878 Lower Mississippi Valley yellow fever epidemic

1900s

• 1900–1904 San Francisco plague epidemic
• 1916 New York City polio epidemic
• 1918–1930 Encephalitis lethargica epidemic
• 1924 Los Angeles pneumonic plague outbreak
• 1924–1925 Minnesota smallpox epidemic
• 1947 New York City smallpox outbreak
• 1962-1965 rubella epidemic
• 1976 Philadelphia Legionnaires' disease outbreak
• 1976 swine flu outbreak
• 1987 Carroll County cryptosporidiosis outbreak
• 1990–1991 Philadelphia measles outbreak
• 1993 Four Corners hantavirus outbreak
• 1992–1993 Jack in the Box E. coli outbreak
• 1993 Milwaukee cryptosporidiosis outbreak
• 1996 Odwalla E. coli outbreak

2000s

• 2003 Chi-Chi's hepatitis A outbreak
• 2003 Midwest monkeypox outbreak
• 2008 United States salmonellosis outbreak
• 2009 swine flu pandemic in the United States
• 2011 United States listeriosis outbreak
• 2012 outbreak of Salmonella
• 2012–2013 United States flu season
• 2014 enterovirus D68 outbreak
• 2015 Bronx Legionnaires' disease outbreaks
• 2015 United States E. coli outbreak
• 2015 United States H5N2 outbreak
• 2016 United States Elizabethkingia outbreak
• 2017–2018 United States flu season
• 2018 United States adenovirus outbreak
• 2019 New York measles outbreak
• 2019 Pacific Northwest measles outbreak
• 2019 United States hepatitis A outbreak
• 2019–2020 United States flu season
• 2020-2023 COVID-19 (national emergency terminated April 2023)
• 2022–2023 mpox outbreak in New York (state)
• 2022–2023 United States P. aeruginosa outbreak in eye drops

See also

• List of epidemics and pandemics
• List of disasters in the United States by death toll

References