This page lists substances used in ritual context.
Psychoactive substances may be illegal to obtain, while non-psychoactive substances are legal, generally.
This sections lists entheogens; drugs that are consumed for their intoxicating effect in combination with spiritual practice.
This is a list of species and genera that are used as entheogens or are used in an entheogenic concoction (such as ayahuasca). For ritualistic use they may be classified as hallucinogens. The active principles and historical significance of each are also listed to illustrate the requirements necessary to be categorized as an entheogen. The psychoactive substances are usually classified as soft drugs in terms of drug harmfulness.
Many man-made chemicals with little human history have been recognized to catalyze intense spiritual experiences, and many synthetic entheogens are simply slight modifications of their naturally occurring counterparts. Some synthetic substances like 4-AcO-DMT are thought to be prodrugs that metabolize into psychoactive substances that have been used as entheogens. While synthetic DMT and mescaline are reported to have identical entheogenic qualities as extracted or plant-based sources, the experience may wildly vary due to the lack of numerous psychoactive alkaloids that constitute the material. This is similar to how isolated THC produces very different effects than an extract that retains the many cannabinoids of the plant such as cannabidiol and cannabinol. A pharmaceutical version of the entheogenic brew ayahuasca is called Pharmahuasca.
This page lists non-psychedelic psychoactive substances which are consumed in ritual contexts for their consciousness-altering effects. Non-psychoactive consumption like symbolic ingestion of psychoactive substances is not mentioned here.
This is a list of psychoactive substances which are consumed in ritual contexts for their consciousness-altering effects. Some of these drugs are classified as hard drugs in terms of drug harmfulness.
The plant parts are listed to prevent accidents. For example, kava roots should always be used because the leaves of the plant are known to cause hepatoxicity and death.
Shown in the table below, Aztec tobacco, morning glories, and Syrian rue (also listed in the table), and cacao beans are (mildly) psychoactive when consumed.