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L-759,633

L-759,633 is an analgesic drug that is a cannabinoid agonist. It is a fairly selective agonist for the CB<sub>2</sub> receptor, with selectivity of 163x for CB<sub>2</sub> over CB<sub>1</sub>.

It produces some similar effects to other cannabinoid agonists such as analgesia, but with little or no sedative or psychoactive effects due to its weak CB<sub>1</sub> activity, and a relatively strong antiinflammatory effect due to its strong activity at CB<sub>2</sub>.

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