Khlong Phra Udom (, ) is one of the twelve subdistricts (tambon) of Pak Kret District in Nonthaburi Province, Thailand. It is bounded by (clockwise from the north) Khlong Khoi, Bang Tanai, Ko Kret and Bang Phlap subdistricts. In 2020 its population was 6,648.
The subdistrict is subdivided into 6 administrative villages (muban).
The whole area of the subdistrict is covered by Khlong Phra Udom Subdistrict Administrative Organization ().