Isoflavone 7-O-glucosyltransferase () is an enzyme that catalyzes several related chemical reaction that convert a phenolic hydroxy group in isoflavones to their glycosyl derivative.
The substrates of this enzyme are an isoflavone and UDP-glucose. These produce the corresponding isoflavone 7-O-beta-D-glucoside and the by-product uridine diphosphate (UDP). For example, daidzein is converted to daidzin.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase, UDPglucose-favonoid 7-O-glucosyltransferase, and UDPglucose:isoflavone 7-O-glucosyltransferase. This enzyme participates in isoflavonoid biosynthesis.