Grumello Cremonese ed Uniti (Cremunés: ) is a comune (municipality) in the Province of Cremona in the Italian region Lombardy, located about southeast of Milan and about northwest of Cremona. Grumello Cremonese ed Uniti borders the following municipalities: Acquanegra Cremonese, Annicco, Cappella Cantone, Crotta d'Adda, Pizzighettone, Sesto ed Uniti.