Greece competed as the host nation of the 2004 Summer Paralympics in Athens, Greece. The team included 124 athletes, 107 men and 17 women. Competitors from Greece won 20 medals, including 3 gold, 13 silver and 4 bronze to finish 34th in the medal table.
|- |align=left|Romaios Roumeliotis |align=left|Men's individual standing |469 |22 |<br />L 116-147 |colspan=5|did not advance
|- |align=left|Anna Tzika |align=left|Women's individual standing |549 |7 | |<br />W 130-128 |<br />L 91-101 |colspan=3|did not advance
The men's football 5-a-side team didn't win any medals, they defeated by Spain in the bronze medal match.
The men's goalball team didn't win any medals, they were 12th out of 12 teams.
The women's goalball team didn't win any medals, they were knocked out in the preliminaries.
The men's volleyball team didn't win any medals, they were 8th out of 8 teams.
The men's team didn't any medals, they were 12th out of 12 teams.