Dr. Livingstone, I presume may refer to:
- Dr. Livingstone, I presume?, a famous greeting by Henry Morton Stanley upon locating David Livingstone in present-day Tanzania
- "Dr. Livingstone, I Presume" (song), a song from 1968 by The Moody Blues
- "Dr. Livingstone (I Presume)", a song by The Tangent from the 2017 album The Slow Rust of Forgotten Machinery
- "Dr. Livingstone (I Presume)", a song by System 7 from the 1994 album Point 3
- Livingstone, I Presume? (video game), also called Livingstone, Supongo, a 1986 game about African exploration by Opera Soft, resp. Alligata