Darengun Rural District () is in Siyakh Darengun District of Shiraz County, Fars province, Iran. Its capital is the village of Hoseynabad, whose population at the time of the 2016 National Census was 1,621 in 440 households.
After the 2016 census, Siyakh Darengun Rural District was separated from the Central District in the establishment of Siyakh Darengun District. Darengun Rural District was created in the new district.