The Central District of Shiraz County () is in Fars province, Iran. Its capital is the city of Shiraz.
In 2009, Sadra was upgraded to city status. After the 2016 National Census, Siyakh Darengun Rural District was separated from the district in the formation of Siyakh Darengun District.
In 2024, Darian Rural District and the city of Darian were separated from the district to form Darian District.
At the time of the 2006 census, the district's population was 1,442,842 in 372,838 households. The following census in 2011 counted 1,625,807 people in 461,209 households. The 2016 census measured the population of the district as 1,788,411 inhabitants in 543,807 households.