Chile competed at the 2020 Summer Paralympics from 24 August to 5 September 2021.
Chile qualified one female archer. Mariana Zuñiga qualified by winning gold at the Pan American Championships in Monterrey, Mexico.
Four Chilean athlete has qualified to compete at the 2020 Summer Paralympics (three women and one man).
One Chilean paracanoeist has qualified to compete at the 2020 Summer Paralympics after being placed in the top five at the 2019 ICF Canoe Sprint World Championships.
Two Chilean male swimmers has qualified to compete at the 2020 Summer Paralympics via MQS.
Two Chilean table tennis players have qualified to compete at the 2020 Summer Paralympics after winning gold medals at the 2019 Parapan American Games and one qualified via World Ranking allocation. Matias Pino was stripped off his Paralympic slot when he was convicted of a doping violation by taking octopamine in August 2019 which resulted in him losing two medals at the Parapans and his Paralympic slot was given to the United States.
Chile qualified three player entries for wheelchair tennis. Two of them qualified through the world rankings, while the other qualified under the bipartite commission invitation allocation quota.