The United States competed at the 2020 Summer Paralympics in Tokyo, Japan from 24 August to 5 September 2021.
Eric Bennett, Lia Coryell, Kevin Mather, KJ Polish, Emma Rose Ravish, Andre Shelby and Matt Stutzman have all qualified.
35 male athletes and 26 female athletes have been selected to compete.
Joseph Berenyi, Clara Brown, Alicia Dana, Thomas Davis, Alfredo de los Santos, Will Groulx, Cody Jung, Oksana Masters, Shawn Morelli, Christopher Murphy, Eric Pinney, Matthew Rodriguez, Monica Sereda, Jill Walsh and Jamie Whitmore have all qualified to compete.
Rebecca Hart, Beatrice Lasnier De Lavalette, Kate Shoemaker and Roxanne Trunnell have all qualified to compete.
Katie Davis, Ben Goodrich, Maria Liana Mutia and Robert Tanaka have all qualified to compete.
Kaitlyn Verfuerth and Blake Haxton have both qualified to compete. Haxton is also going to compete in rowing.
Seven paratriathletes have qualified to compete.
Jacob Schrom has qualified to compete.
U.S. qualified four boats for all of the rowing classes into the Paralympic regatta. All of them qualified after successfully entering the top seven for single sculls events and top eight for mixed events at the 2019 World Rowing Championships in Ottensheim, Austria.
<small>Qualification Legend: FA=Final A (medal); FB=Final B (non-medal); R=Repechage</small>
Jazmin-Almlie-Ryan, Stetson Bardfield, Taylor Farmer, McKenna Geer, Yan Xiao Gong, John Joss and Kevin Nguyen have all qualified to compete.
The women's sitting volleyball team qualified for the 2020 Summer Paralympics after their results at the 2018 World ParaVolley Championships.
34 American swimmers are qualified to compete in the Paralympics.
United States entered three athletes into the table tennis competition at the games. Ian Seidenfeld & Tahl Leibovitz qualified from 2019 Parapan American Games which was held in Lima, Peru and Jenson Van Emburgh via World Ranking allocation.
Para taekwondo makes its debut appearance in the Paralympic programme, Evan Medell & Brianna Salinaro, qualified to the 2020 Summer Paralympics via World Ranking.
Ellen Geddes, Terry Hayes and Shelby Jensen have all qualified to compete.
United States national wheelchair rugby team qualified for the Games for the games by winning the gold medal at the 2019 Parapan American Games in Lima, Peru.
U.S. qualified seven players entries for wheelchair tennis. Five of them qualified by world ranking, while the other qualified by received the bipartite commission invitation allocation quotas.