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CUMYL-PICA

CUMYL-PICA (SGT-56) is an indole-3-carboxamide based synthetic cannabinoid. It is the α,α-dimethylbenzyl analogue of SDB-006. It was briefly sold in New Zealand during 2013 as an ingredient of at the time legal synthetic cannabis products, but the product containing CUMYL-BICA and CUMYL-PICA was denied an interim licensing approval under the Psychoactive Substances regulatory scheme, due to reports of adverse events in consumers. CUMYL-PICA acts as an agonist for the cannabinoid receptors, with K<sub>i</sub> values of 59.21&nbsp;nM at CB<sub>1</sub> and 136.38&nbsp;nM at CB<sub>2</sub> and EC<sub>50</sub> values of 11.98&nbsp;nM at CB<sub>1</sub> and 16.2&nbsp;nM at CB<sub>2</sub>.

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