2C-B-3PIP-NBOMe is a serotonin receptor modulator of the phenethylamine, 2C, 3-phenylpiperidine (3PIP), and NBOMe families. It is a cyclized phenethylamine and along with 2C-B-3PIP-POMe is an NBOMe derivative of 2C-B-3PIP. The drug shows very weak affinity for the serotonin 5-HT<sub>2A</sub> and 5-HT<sub>2C</sub> receptors (K<sub>i</sub> = 2,150nM and 5,880nM, respectively), with its affinities being profoundly reduced relative to those of 2C-B. The chemical synthesis of 2C-B-3PIP-NBOMe has been described. 2C-B-3PIP-NBOMe was first described in the scientific literature by Martin Hansen in 2010.