The 2010 season of the Meistriliiga, the first level in the Estonian football system, was the 20th season in the league's history. It started in March and ended in November. The defending champions were Levadia.
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The 9th placed team of Meistriliiga, Kuressaare, and the fourth place team of Esiliiga, Kiviõli Tamme Auto competed in a two-legged relegation play-off for one spot in 2011 Meistriliiga. Kuressaare won the play-off 4âÂÂ2 on aggregate and retained their spot in the league.
Each team played every opponent four times, twice at home and twice on the road, for a total of 36 games.
Sander Post was named Meistriliiga Player of the Year.