The 2010 season of the Esiliiga, the second level in the Estonian football system, is the 20th season in the league's history. It starts in March and ends in November. The defending champions are Levadia II, who are unable for promotion as they are the reserve team for Meistriliiga side Levadia.
Each team plays every opponent four times, twice at home and twice on the road, for a total of 36 games.