(S)-limonene 6-monooxygenase

(S)-limonene 6-monooxygenase () is an enzyme that catalyzes the chemical reaction

The four substrates of this enzyme are (−)-(S)-limonene, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen and a proton. Its products are (−)-trans-carveol, oxidised NADP, and water.

This enzyme is a cytochrome P450 protein containing heme. This oxidoreductase, which uses molecular oxygen as oxidant is in a group with systematic name (S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating). Other names in common use include (−)-limonene 6-hydroxylase, (−)-limonene 6-monooxygenase, and (−)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating). It is part of the biosynthetic pathway that leads to (−)-carvone, a compound giving spearmint its aroma.

See also

• CYP2C19
• (R)-limonene 6-monooxygenase which converts the opposite enantiomer of limonene to (+)-trans-carveol

References