Vanadocene dichloride is an organometallic complex with formula (÷<sup>5</sup>-C<sub>5</sub>H<sub>5</sub>)<sub>2</sub>VCl<sub>2</sub> (commonly abbreviated as Cp<sub>2</sub>VCl<sub>2</sub>). It is a structural analogue of titanocene dichloride but with vanadium(IV) instead of titanium(IV). This compound has one unpaired electron, hence Cp<sub>2</sub>VCl<sub>2</sub> is paramagnetic. Vanadocene dichloride is a suitable precursor for variety of bis(cyclopentadienyl)vanadium(IV) compounds.
Cp<sub>2</sub>VCl<sub>2</sub> was first prepared by Wilkinson and Birmingham via the reaction of NaC<sub>5</sub>H<sub>5</sub> and VCl<sub>4</sub> in THF.
The compound has been used in organic synthesis.
Reduction of vanadocene dichloride gives vanadocene, (C<sub>5</sub>H<sub>5</sub>)<sub>2</sub>V.
Like titanocene dichloride, this organovanadium compound was investigated as a potential anticancer drug. It was conjectured to function by interactions with the protein transferrin.