Valine dehydrogenase (NAD<sup>+</sup>) () is an enzyme with systematic name L-valine:NAD<sup>+</sup> oxidoreductase (deaminating). This enzyme catalyses the following chemical reaction
The enzyme from Streptomyces spp. uses nicotinamide adenine dinucleotide as its cofactor but has no activity with NADP<sup>+</sup>.