Valerena-4,7(11)-diene synthase (EC 4.2.3.139, VoTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, valerena-4,7(11)-diene-forming). This enzyme catalyses the following chemical reaction
This enzyme is isolated from the plant Valeriana officinalis (valerian).