The enzyme uracil-5-carboxylate decarboxylase () catalyzes the chemical reaction
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is uracil-5-carboxylate carboxy-lyase (uracil-forming). Other names in common use include uracil-5-carboxylic acid decarboxylase, and uracil-5-carboxylate carboxy-lyase.