Trimethylsulfonium (systematically named trimethylsulfanium) is an organic cation with the chemical formula (also written as ).
Several salts of trimethylsulfonium are known. X-ray crystallography reveals that the ion has trigonal pyramidal molecular geometry at sulfur atom, with C-S-C angles near 102ð and C-S bond distance of 177 picometers. Unless the counteranion is colored, all trimethylsulfonium salts are white or colorless.
Sulfonium compounds can be synthesised by treating a suitable alkyl halide with a thioether. For example, the reaction of dimethyl sulfide with iodomethane yields trimethylsulfonium iodide:
An extra oxygen atom can bond to the sulfur atom to yield the trimethylsulfoxonium ion , where the sulfur atom is tetravalent and tetracoordinated.
Glyphosate herbicide is often supplied as a trimethylsulfonium salt, referred to as trimesium.
When mixed with aluminium bromide, or aluminium chloride or even hydrogen bromide, trimethylsulfonium bromide forms an ionic liquid, which melts at temperatures below standard conditions.