trans-o-Hydroxybenzylidenepyruvate hydratase-aldolase (, 2â²-hydroxybenzalpyruvate aldolase, NsaE, tHBPA hydratase-aldolase) is an enzyme with systematic name (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase. This enzyme catalyses the following chemical reaction
This enzyme is involved in naphthalene degradation.