In enzymology, a trans-acenaphthene-1,2-diol dehydrogenase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are (+/-)-trans-acenaphthene-1,2-diol and NADP<sup>+</sup>, whereas its 3 products are acenaphthenequinone, NADPH, and H<sup>+</sup>.
This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is . This enzyme is also called .