Thyronamine

Thyronamine is a type of decarboxylated and deiodinated metabolite of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3). The word thyronamine can refer to either the family of molecules, or the specific molecule from which they are derived.

Types

The group includes:

• Thyronamine (T0AM)
• 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), an intracellular G protein-coupled receptor
• 3,5-Diiodothyronamine (T2AM)
• 3,5,3'-Triiodothyronamine (T3AM)

See also

• Trace amines
• Thyroid hormone

References