Thiomyristoyl is a drug which acts as a potent sirtuin 2 (SIRT2) inhibitor. It inhibits SIRT2 with an IC<sub>50</sub> of 28 nM, though its activity at other SIRT subtypes has not been well characterized. It has beneficial effects in an animal model of ulcerative colitis, and is also used for studying the role of SIRT2 in cancer progression.