Dimethylthiocarbamoyl chloride is an organosulfur compound with the formula (CH<sub>3</sub>)<sub>2</sub>NC(S)Cl. A yellow solid, it is often encountered as a yellow syrup. It is a key reagent in the synthesis of arylthiols via the Newman-Kwart rearrangement.
Representative of other thiocarbamoyl chlorides, dimethylthiocarbamoyl chloride is electrophilic, serving as a source of R<sub>2</sub>NC(S)<sup>+</sup>. It is analogous to dimethylcarbamoyl chloride (R<sub>2</sub>NC(O)Cl).
Dimethylthiocarbamoyl chloride is prepared by chlorination of the related tetramethylthiuram disulfide:
Dimethylthiocarbamoyl chloride reacts with dithiocarbamates (R<sub>2</sub>NCS) to give thiuram sulfides [R<sub>2</sub>NC(S)]<sub>2</sub>S. With methanethiolate, it gives methyl dimethyldithiocarbamate (Me<sub>2</sub>NC(S)SMe).