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Tetramer

A tetramer () (', "four" + ', "parts") is an oligomer formed from four monomers or subunits. The associated property is called tetramery. An example from inorganic chemistry is titanium methoxide with the empirical formula Ti(OCH<sub>3</sub>)<sub>4</sub>, which is tetrameric in solid state and has the molecular formula Ti<sub>4</sub>(OCH<sub>3</sub>)<sub>16</sub>. An example from organic chemistry is kobophenol A, a substance that is formed by combining four molecules of resveratrol.

In biochemistry, it similarly refers to a biomolecule formed of four units, that are the same (homotetramer), i.e. as in Concanavalin A or different (heterotetramer), i.e. as in hemoglobin. Hemoglobin has 4 similar sub-units while immunoglobulins have 2 very different sub-units. The different sub-units may have each their own activity, such as binding biotin in avidin tetramers, or have a common biological property, such as the allosteric binding of oxygen in hemoglobin.

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