In enzymology, taurine dehydrogenase () is an enzyme that catalyzes the chemical reaction.
The 3 substrates of this enzyme are taurine, water, and an electron acceptor. Its products are sulfoacetaldehyde, ammonia, and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH<sub>2</sub> group of donors with other acceptors. The systematic name of this enzyme class is taurine:acceptor oxidoreductase (deaminating). This enzyme is also called taurine:(acceptor) oxidoreductase (deaminating). This enzyme participates in nitrogen metabolism.