TRNA1Val (adenine<sup>37</sup>-N<sup>6</sup>)-methyltransferase (, YfiC) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA1Val (adenine<sup>37</sup>-N<sup>6</sup>)-methyltransferase. This enzyme catalyses the following chemical reaction
The enzyme specifically methylates adenine<sup>37</sup> in tRNA1Val (anticodon cmo5UAC).