TRNA-dihydrouridine47 synthase (NAD(P)<sup>+</sup>) (, Dus3p, tRNA-dihydrouridine synthase 3) is an enzyme with systematic name tRNA-5,6-dihydrouracil47:NAD(P)<sup>+</sup> oxidoreductase. This enzyme catalyses the following chemical reaction
This enzyme specifically modifies uracil47 in tRNA.