In enzymology, a succinylglutamate desuccinylase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are N-succinyl-L-glutamate and H<sub>2</sub>O, whereas its two products are succinate and L-glutamate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-succinyl-L-glutamate amidohydrolase. Other names in common use include N2-succinylglutamate desuccinylase, SGDS, and AstE. This enzyme participates in arginine and proline metabolism.